Senior & Staff Bioinformatics Scientist's

, developing next-generation bioinformatics solutions that turn complex genomic data into meaningful biological insights.

We have multiple opportunities where you will tackle some of the most exciting and meaningful challenges in genomics, working at the intersection of science, software, and innovation. Your work will help drive breakthroughs in areas including rare disease, oncology, population genomics, and precision medicine.

Why these roles?

At Illumina, innovation is driven by purpose. Every project, algorithm, and advancement contributes to a mission that matters: improving human health through genomics. You'll work alongside world-class scientists, engineers, and cross-functional partners to develop technologies that have a real-world impact on patients and communities around the globe.

You'll have the opportunity to:

• Design novel algorithms that advance genomic analysis at scale
• Contribute to one of the most widely adopted secondary analysis platforms in sequencing
• Collaborate with leading experts across software engineering, FPGA development, clinical genomics, quality, and customer-facing teams
• Solve complex scientific challenges while helping shape the future direction of genomic technologies
• Deliver solutions that support discoveries, diagnostics, and precision medicine applications worldwide

About You

You're a curious and innovative scientist who thrives on solving complex biological and computational challenges.

You combine deep expertise in bioinformatics, genomics, statistics, and algorithm development with a passion for translating cutting-edge research into production-ready solutions. Whether working independently or collaborating across disciplines, you're motivated by meaningful challenges and excited by the opportunity to create tools that make a tangible difference.

You will likely bring:

• A Master's or PhD in Bioinformatics, Computer Science, Statistics, Engineering, or a related discipline
• Strong experience developing bioinformatics methods and algorithms for next-generation sequencing data
• Expertise in secondary analysis workflows including mapping, alignment, variant calling, and genomic interpretation
• Proficiency in C/C++, or equivalent high-performance programming languages
• Experience working with large-scale genomic datasets and production software environments
• Knowledge of applications such as cancer genomics, rare disease analysis, population genetics, transcriptomics, or multi-omics research

Most importantly, you're excited by the opportunity to push boundaries, redefine what's possible, and help deliver genomic insights that improve lives.

• Design, develop, and implement innovative computational and statistical methods for genomic data analysis
• Build high-performance production software that delivers speed, scalability, and accuracy
• Analyze and interpret complex sequencing datasets to support product and workflow development
• Partner with software, FPGA, quality, clinical genomics, and product teams to deliver integrated solutions
• Advance the DRAGEN platform across germline, somatic, DNA, RNA, structural variant, CNV, and targeted sequencing applications
• Engage with customers, researchers, and scientific collaborators to understand emerging needs
• Present scientific findings and technical approaches to both specialist and non-specialist audiences
• Contribute to publications, presentations, technical documentation, and thought leadership initiatives
• Evaluate and apply emerging technologies to continuously improve performance and customer outcomes
• Champion collaboration, accountability, and innovation while helping teams succeed together