Senior Expert Science & Technology – Downstream Process Development (m/f/d) - Razvoj procesov čiščenja učinkovin dodaj naslov Povzetek opisa delovnega mesta (m/ž/d)

• Lead and coordinate downstream process development activities across assigned portfolio projects, independently managing multiple priorities and ensuring high-quality delivery within agreed timelines and project requirements.
• Independently design, plan, execute and document laboratory studies for the development and optimization of robust purification processes for recombinant proteins, applying a right-first-time approach.
• Perform and optimize DSP processes and methods, and evaluate opportunities to implement new technologies.
• Manage, analyze and interpret experimental data; draw scientifically sound conclusions, define follow-up studies, and lead troubleshooting for complex process challenges.
• Prepare high-quality protocols, technical reports, laboratory procedures, SOPs, development documentation, handover packages and regulatory-relevant deliverables.
• Act as DSP scientific or functional lead in local and global cross-functional project teams, providing expert recommendations and supporting evidence-based development decisions.
• Support process scale-up, technology transfer and implementation at internal or external manufacturing sites, including knowledge transfer and definition of process controls.
• Advance DSP capabilities through automation, process modelling, digitalization, data science and AI-enabled development approaches.
• Communicate scientific results, achievements, risks and recommendations effectively to project teams, stakeholders and external partners, and contribute to publications, patents and scientific conferences, as appropriate.
• Mentor colleagues, support laboratory organization and advanced DSP equipment activities, and ensure compliance with applicable quality, ethics, health, safety, environmental and information-security requirements.

• PhD in Biotechnology, Biochemical or Chemical Engineering, Biochemistry, Biology, Pharmaceutical Technology or a related scientific or engineering discipline with at least 3 years of relevant experience in DSP development and/or manufacturing; alternatively, an MSc with at least 5 years of relevant experience.
• Strong hands-on expertise in downstream process development, with sound knowledge of process parameters, scale-down and scale-up principles, and integrated unit operations.
• Demonstrated ability to independently design, execute, document and interpret complex experiments, apply appropriate data analysis methods, troubleshoot process challenges and translate results into clear development decisions.
• Proven ability to manage multiple priorities and deliver high-quality results within agreed timelines, while working effectively in local and global cross-functional, matrix-based project teams.
• Experience with data science, modelling, digital tools or automation in process development, together with a strong interest in advancing AI-enabled approaches within the DSP team.
• Strong scientific and technical communication skills, with the ability to understand scientific and business needs and translate them into clear, practical recommendations and development strategies.
• Fluent written and spoken English, combined with a responsible, objective-driven and collaborative approach; previous scientific or technical leadership experience is an advantage.

Depending on the selected candidate's knowledge, experience, competencies, and seniority, the company reserves the right to appoint the candidate to a position at a lower level than the one specified in the job posting, namely the

• Vodili in usklajevali aktivnosti razvoja procesov izolacije in čiščenja bioloških učinkovin v okviru dodeljenih projektov ter zagotavljali kakovostno izvedbo v dogovorjenih rokih.
• Samostojno načrtovali, izvajali in dokumentirali laboratorijske študije za razvoj, optimizacijo in karakterizacijo robustnih procesov čiščenja, zlasti kromatografskih in filtracijskih stopenj.
• Analizirali in interpretirali eksperimentalne podatke, oblikovali znanstveno utemeljene zaključke, načrtovali nadaljnje študije ter vodili reševanje kompleksnih procesnih izzivov.
• Uporabljali modeliranje, podatkovno znanost, avtomatizacijo, digitalna orodja in pristope umetne inteligence za podporo načrtovanju procesov, povečevanju merila, vrednotenju robustnosti in odločanju.
• Ocenjevali nove tehnologije in razvojne pristope ter vodili njihovo smiselno uvedbo v laboratorijske procese in delovne tokove DSP.
• Delovali kot strokovni ali funkcijski vodja za področje DSP v lokalnih in globalnih medfunkcijskih projektnih ekipah ter zagotavljali jasna strokovna priporočila.
• Podpirali povečevanje merila, prenos tehnologije in uvedbo procesov na pilotnih oziroma proizvodnih lokacijah, vključno s prenosom znanja in opredelitvijo procesnih kontrol.
• Pripravljali kakovostne protokole, tehnična poročila, laboratorijske in standardne operativne postopke, razvojno dokumentacijo, pakete za prenos ter prispevke za regulatorne dokumente.
• Jasno predstavljali rezultate, tveganja in priporočila notranjim ter zunanjim deležnikom ter po potrebi prispevali k publikacijam, patentom in znanstvenim konferencam.
• Mentorirali sodelavce, prispevali k učinkoviti organizaciji laboratorijskega dela in zagotavljali skladnost z zahtevami kakovosti, etike, zdravja, varnosti, okolja ter informacijske varnosti.

• Doktorat s področja biotehnologije, biokemije, kemijskega ali biomedicinskega inženirstva, farmacevtske tehnologije oziroma sorodne naravoslovne ali tehniške smeri ter najmanj 3 leta relevantnih izkušenj; alternativno magisterij z najmanj 5 leti ustreznih izkušenj.
• Poglobljeno praktično znanje razvoja procesov izolacije in čiščenja bioloških učinkovin, vključno s procesnimi parametri, povečevanjem in zmanjševanjem merila ter povezovanjem procesnih stopenj.
• Sposobnost samostojnega načrtovanja, izvedbe, dokumentiranja in interpretacije kompleksnih eksperimentov ter pretvorbe rezultatov v znanstveno utemeljene razvojne odločitve.
• Izkušnje z analizo podatkov, modeliranjem, digitalnimi orodji ali avtomatizacijo ter interes za uporabo podatkovne znanosti in umetne inteligence pri razvoju procesov.
• Sposobnost učinkovitega reševanja kompleksnih procesnih izzivov, obvladovanja več prednostnih nalog in zagotavljanja kakovostnih rezultatov v dogovorjenih rokih.
• Odlične znanstvene in tehnične komunikacijske sposobnosti ter učinkovito sodelovanje v lokalnih in globalnih medfunkcijskih ekipah v matričnem okolju.

Glede na znanje, izkušnje in kompetence izbranega kandidata oziroma kandidatke si pridržujemo pravico do ponudbe zaposlitve na delovnem mestu, uvrščenem na nižjo raven od razpisane, in sicer na delovno mesto

At Novartis, we're committed to reimagining medicine together - and rewarding the people who make it happen.

Expected Annual Base Salary Range for role:

• Slovenia: €46,550 - €86,450

The salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.

Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.

In addition to your base salary, you will be eligible for benefits listed below: •

A program offering confidential, personalized support for mental health and well-being through therapy, counselling, tools, and more.

• Other benefits in accordance with legislation and collective agreements:

Prijavo oddajte z življenjepisom v slovenskem in angleškem jeziku.

V Novartisu smo zavezani k soustvarjanju prihodnosti medicine ter priznavanju in nagrajevanju ljudi, ki to omogočajo.

Pričakovani letni osnovni razpon plače za delovno mesto:

• Slovenija: €46,550 - €86,450

Osnovna plača se določa na podlagi vnaprej opredeljenih in transparentnih kriterijev, kot so relevantne veščine, kompetence in izkušnje, ne glede na spol, ter v skladu z Novartisovo politiko določanja plač. Po zaposlitvi v Novartisu se plača periodično pregleda v skladu z internimi akti in postopki.

Plačna enakost je temeljno načelo naše kadrovske politike in odraža našo zavezo k ustvarjanju raznolikega, pravičnega in vključujočega okolja, ki vse zaposlene obravnava dostojanstveno in spoštljivo, kot je opredeljeno v našem Kodeksu etike.

Poleg osnovne letne bruto plače so zaposleni upravičeni tudi do spodaj navedenih ugodnosti: •

Program, ki ponuja zaupno, osebno podporo za vaše duševno zdravje in dobro počutje s pomočjo terapij, svetovanj, orodij in še mnogo več.

• Ostale ugodnosti v skladu z zakonom in kolektivno pogodbo: