Senior Scientist I/II, Pharmaceutical Development – Thermodynamics & AI/ML Applications (all genders) (fulltime, regular)
About the role
About AbbVie
Job Description
Together, we break through – as
About the role
- Develop and apply predictive models to guide formulation and process development decisions across pharmaceutical programs.
- Apply thermodynamic and quantum mechanical principles to predict key material and product behaviors such as solubility, phase behavior, crystallization, supersaturation, and moisture sensitivity.
- Build and improve models for physical stability, material compatibility, excipient interactions, and process-related performance of drug substances and drug products.
- Create and implement practical tools and workflows using hybrid physics-based and machine learning approaches that integrate mechanistic insight with experimental and historical data.
- Define and execute robust model validation strategies, including uncertainty assessment, applicability domain evaluation, and clear performance documentation.
- Convert complex datasets into actionable insights for formulation selection, risk assessments, experiment prioritization, and overall development strategy.
- Communicate model findings, assumptions, limitations, and recommendations clearly to both technical and non-technical stakeholders while supporting modeling best practices and reproducibility.
- Work closely with thermodynamic modeling experts, internal modeling teams, and laboratory scientists to ensure model development addresses real-world development needs.
Qualifications
This is how you make a difference
- Advanced degree (PhD) in pharmaceutical sciences, chemical engineering, physical chemistry, materials science, data science for physical systems or related disciplines.
- Strong understanding of thermodynamics and its application to pharmaceutical materials, formulations, and process performance.
- Proven ability to perform quantitative modeling and analyze and interpret physicochemical experimental data.
- Experience using AI/ML for scientific or engineering problems, with focus on data quality, model suitability, and interpretability.
- Ability to combine mechanistic insight with data-driven methods to address real-world development challenges.
- Proficiency in structuring analyses, documenting methods, and presenting conclusions in a business-relevant manner.
- Strong collaboration and professional communication skills for working across cross-functional, technical, and international teams.
- Excellent written and verbal communication skills in English
What we offer you
- with a diverse work environment where you can have a real impact
- with an open corporate culture
- with an attractive salary
- with an intensive onboarding process with a mentor at your side
- with flexible work models for a healthy work-life balance
- with a corporate health management that offers comprehensive health and exercise programs
- with company social benefits
- with a wide range of career opportunities in an international organization
- with top-tier, attractive development opportunities
- with a strong international network
At multiple times, we have been globally recognized as a "Great Place to Work" and we are proud to provide our employees with the flexibility to maintain a healthy work-life balance. We take our impact on the environment and our communities seriously and therefore focus on giving something back on a regular basis. We are committed to equality, equity, diversity and inclusion (EED&I) - a commitment that is fundamental to us. This includes appreciating different perspectives, creating an inclusive culture and treating all employees with dignity and respect. At AbbVie, your individual contributions count - help us move mountains together. Be a part of our success, grow with us and accomplish more than you could have imagined. Sounds like the perfect career opportunity for you? We look forward to receiving your application! All you need is a complete CV - we will discuss everything else with you in person. Any questions? Feel free to email Talentacquisition.de@abbvie.com - We look forward to hearing from you!
Additional Information
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html
Not included in the source posting: qualifications.
Skills
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