Senior Scientist in Flow Cytometry

The Flow Cytometry Technology Platform in the 360 Labs Initiative is seeking an experienced, highly motivated, collaborative, and customer-centric lab-based senior scientist. The successful candidate will possess deep expertise across the entire flow cytometry workflow, from complex sample preparation to high-parameter data analysis and advanced instrument troubleshooting, along with a proven track record in assay development and validation. Experience in multidisciplinary, multi-omic projects (integrating flow cytometry with genomics, proteomics, or imaging) is highly desirable. You will work with a sense of urgency as a part of a matrix team, collaborating with specialists from each of our therapeutic disease areas and functions to propel drug discovery projects forward. You will also contribute to the ongoing development and operations of the Flow Cytometry Technology Platform within the pRED organisation.

Your Role and Responsibilities:

• You will work closely with research teams across pRED's therapeutic areas to advance drug discovery projects through expert flow cytometry support. This includes collaborating on high-parameter panel design (up to 40+ parameters), advanced data analysis and interpretation, and consulting on how flow cytometry, including functional assays and emerging applications, can best be leveraged within pharma R&D;
• You will coordinate and execute, in collaboration with the rest of the flow cytometry team, daily quality control on instruments, monitor results for accuracy, and conduct regular maintenance and troubleshooting on equipment to ensure the continual generation of high-quality experimental data;
• You will deliver multi-tiered training and user onboarding to enable independent analyser operation, as well as provide high-speed cell sorting as a core service for complex biological samples (e.g., primary tissues and organoids) through expert, independent operation of cell sorters;
• You will embrace a culture of continuous learning by actively engaging with the latest scientific literature to stay at the forefront of emergent flow cytometry-based technologies and approaches; present findings and updates to internal stakeholders and at scientific conferences (where appropriate), ensuring cutting-edge expertise is cultivated and maintained.

• You hold a PhD degree in Biology, Biochemistry, Chemistry, or a related field, with at least 3-5 years of professional experience working within a flow cytometry-intensive research laboratory or shared resource laboratory.
• You possess in-depth knowledge of flow cytometry with practical experience in designing and executing flow cytometry experiments, as well as high-dimensional bioinformatic data pipelines and semi-automated analysis (e.g. FlowSOM, UMAP). This includes assay development and validation, multicolour spectral panel design, and expertise in imaging flow cytometry, metabolic and functional assays.
• You have extensive hands-on experience with cell sorting for a wide range of different applications.

In addition to your scientific expertise and critical technical skills, we are looking for candidates who are:

• Customer-focused with a drive for growth and a questioning mindset. Skilled in creative problem-solving, organisation, and implementing innovative ideas efficiently in a fast-paced research context;
• Excellent communicators with a high fluency in English, a desire to continuously build a personal network, and the ability to thrive in a dynamic, inclusive environment which gives you full accountability for your own contributions and development.

At Roche, we aim high to deliver life-changing healthcare solutions. If you're ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you.