Scientist I/II, In Vivo Pharmacology – Immuno-oncology

• Design, execute and optimize efficacy/PK/PD studies utilizing tumor models in both immunocompetent and immunocompromised mice.
• Understand and adhere to IACUC protocols regarding animal welfare and handling.
• Data analyses and presentation of pharmacodynamic/disease results, and work across discovery teams to integrate efficient workflows for cross-functional collaborations.
• Commitment to scientific rigor, high data quality and careful documentation.

Qualifications

MS with 5+ years of experience, or BS with 7+ years of experience

• Degree in cancer biology, immunology, pharmacology, or a related with extensive hands-on skills of in vivo tumor model execution; preferably in a pharmaceutical or biotech industry setting.
• Proficient hands-on experience with in vivo pharmacodynamic and tumor models, including anesthetization, biological sample collection (blood, spleen, lymph node, etc.), cell/drug administration via different routes/sites (SC, IP, PO, IV), and tumor volume measurement.
• Technical experience and knowledge in tissue culture and immune cell isolation from lymphoid tissue are desired.
• Knowledge of PK/PD relationships, flow cytometry, and other standard molecular and cellular biology assays (MSD, ELISA, etc.) are advantages.
• Understanding of in vivo optical imaging approaches and familiarity with instrumentation (e.g. IVIS instrument) is also an advantage.
• Must be proactive and able to manage multiple responsibilities, adapt to changing priorities and meet deadlines in a fast-paced environment.
• Excellent verbal and written communication skills and the willingness to work and build strong relationships with peers in a multidisciplinary team are essential.
• Flexibility and motivation to learn techniques and accomplish goals outside those stated above.

Additional Information

​Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​
• This job is eligible to participate in our short-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law. ​

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