Scientist, ADC Oncology Discovery Biology

In the role as a Scientist within Discovery Biology, the ideal candidate:

• Uses current and new techniques for function-based identification and selection of antibody-drug-conjugate (ADC) lead drug candidates

• Applies extensive technical knowledge to address ADC mechanism of action and to establish PD/efficacy relationships

• Designs and executes molecular and cellular studies.

• Collaborates with rest of biology team members as well as other functional area leads e.g. pharmacology, DMPK, informatics and predictive science.

• Presents data in lab meetings as well as full team project meetings.

• Executes experiments independently, troubleshoot as needed, interpret, and discuss data.

• Utilizes excellent communication and interpersonal skills.

• Communicates via email, meetings, and reports.

• Conducts experimental work independently, with accurate, detailed record-keeping.

• Performs laboratory work related but not limited to tissue culture, qPCR, western blot, multi-parametric flow cytometry, immune cell culture using activation/expansion/exhaustion assays, proliferation and tumor killing assays, 2D/3D co-culture activity assays, ELISA, Luminex, processing of DNA/RNA/protein.

• Bachelor's Degree
• 5+ years of academic and / or industry experience

Or

• Master's Degree
• 3+ years of academic and / or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences
• No experience necessary

• Bachelor's/Master's Degree and 1-2 years relevant industry experience.

• Experience in oncology and immuno-oncology biologics drug discovery (antibody-drug-conjugates preferred).

• Proficient with expression modulation tools e.g. CRISPRs, shRNAs, siRNAs.

• Extensive knowledge of flow cytometry, Incucyte and high content imaging platforms

• Experienced in the design, development and optimization of high-throughput cell-based assays for antibody screening and ADC activity

• Ability to efficiently manage and prioritize multiple projects, coordinating in-house research with collaborative work.

• Ability to summarize and interpret scientific data in a clear, concise, and accurate manner.

• Excellent oral and written communication skills. Ability to communicate well with peers and supervisors.

• Strong problem-solving skills and understanding of relevant scientific principles.

#LI-Onsite

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.