[PGS] Sr.Manager, External Supply Operations Lead

-The ES Operations Lead is responsible for the relationship, and for the performance of the CMOs and Partners in his/her area of portfolio which are located primarily within Japan . Short-term tactics as well as long-term strategies must ensure that every CMO contributes to achieving ES EMC Integrated Manufacturing Excellence metrics and strategic objectives. -Lead Virtual Site Operations Teams (VSOTs) and provide matrix leadership to all members of the VSOT including but not limited to ES Quality, PPLs, BSLs, supply chain planners, procurement and GTE project leads. The ES Operations Lead is accountable for the results of the VSOT. The activities and responsibilities of the VSOT include:

• Manage global stakeholders including but not limited to Product Portfolio Leaders, Brand Supply leaders and Commercial and PGS leadership
• Have P&L responsibility for a complex selected portfolio including direct accountability for contract negotiations and external relationship management at CEO level with the contractor base
• Development and execution of manufacturing and supply plans and meet market demand for product and meet or exceed supply performance target; this includes supply of APIs, raw materials and components where appropriate.
• Development and execution of tactical plans for continuous improvement of CMO shop floor performance in the areas of product quality, EH&S, compliance, customer service and cost.
• Review of the status of deviations which impact or may affect product supply. The ES Operations Lead is responsible to secure correct and timely closing of relevant deviations, and when necessary, lead closure of investigations that have not been properly addressed by the CMO.
• Oversee and secure timely execution of new product introduction, product changes (including changes of materials and API), product enhancement, localization and product transfer programs. Lead implementation teams where required.

-Ensure that product supply, quality, compliance and cost issues at CMOs are adequately addressed by making extensive use of Operational Excellence tools and mobilizing the necessary resources for support in all required areas. Lead these cross-functional teams where required. -Collaborate with EH&S to ensure compliance with environmental, health and safety regulations and Pfizer requirements. -Ensure effective communication of key product supply issues to stakeholders, communication with CM Site Leads and Vice Presidents, with PGS PPLs, and with ES Leadership. -Partner with ES Quality to ensure CMOs comply with regulatory requirements, cGMP's, Pfizer Quality Standards and Standard Operating Procedures. -Manage the cost reduction program:

• Identify cost reduction opportunities with CMOs
• Validate the financial impact and secure the opportunities are captured and reported in the Long Range Plan and the Operational Plan
• Oversee execution and implementation, lead the team for execution as appropriate
• Meet or exceed annual budget cost reduction target

-Maintain awareness of potential new sourcing opportunities and identify strategic sourcing partners for the manufacture/packaging/testing of pharmaceutical products who share common vision/values with PGS. -Ensure compliance with Legal Requirements of the "

and related other legislation as directed by the relevant Pfizer Corporate Policies. The ES Operations Lead is accountable for appropriate documentation of compliance with all requirements. -Support and actively participate in ES initiatives to drive the business and to enable delivery of key metrics -Lead assigned project and initiatives for his/her portfolio of contractors including but notlimited to:

• Serialization
• Business Continuity Plans
• Supplier Network Collaboration
• Environmental Sustainability

-20 - 25% travel required (primarily across Japan). KEY PERFORMANCE INDICATORS: 1.Supply performance: meet the targets set under ES Integrated Manufacturing Excellence balanced scorecard. 2.Product cost reduction. 3.Quality: no rejects or recalls due to contract manufacturer errors.

(Preferred Requirements)

• A Master's degree coupled with significant pharmaceutical experience
• Familiarity with industry standards for Good Manufacturing Practices in drug product manufacturing operations.
• Strong understanding of Supply Chain discipline
• Excellent negotiation skills for managing essential contracts and agreements
• Ability to influence and drive teams towards achieving division targets
• High degree of adaptability and problem-solving skills in complex project environments
• Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity. Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .

Manufacturing