E4A Systemic Mastocytosis/Emerging Indication HEOR Strategy Specialist

This role will lead US‑focused Health Economic and Outcomes Research activities for AYVAKIT® in Systemic Mastocytosis and emerging pipeline assets within the US Rare/Oncology HEVA team, providing US insights and executional leadership while remaining aligned to - but not accountable for - global HEVA strategy.

• Lead the design and execution of US-focused HEOR for AYVAKIT® (avapritinib) in Systemic Mastocytosis and assigned emerging assets - including economic modelling, database analysis, observational research, RWE studies, systematic literature review, evidence synthesis, and AMCP dossier development - setting US evidence generation priorities and incorporating them into broader Sanofi planning documents such as the Integrated Evidence Generation Plan (IEGP); operate with medium independence for strategic work and high independence for tactical execution, consistent with L3-2 expectations.
• Translate HEVA evidence into US business and policy impact by driving payer engagement, value positioning, and access strategies for AYVAKIT® in the US marketplace; understand and address US payer evidence requirements across managed care, specialty pharmacy, and rare disease payer dynamics; and support the development of compliant and impactful US evidence dissemination pathways (e.g., HCEI, PIE, CFL) including payer dossiers, field materials, and publications.
• Operate as part of a multi-functional US brand team responsible for designing research programs to meet the evidentiary standards of US reimbursement authorities and third-party payers; provide recommendations to ensure clinical and real-world evidence programs support US payer differentiation and value demonstration; and contribute to cross-functional US planning processes including brand planning, lifecycle management, and launch readiness for AYVAKIT® and pipeline assets.
• Serve as the US HEVA representative within the broader global HEVA team, ensuring the US perspective is well represented in global IEGPs, clinical development programs, and market access strategies; translate global evidence packages into US-specific value narratives and payer-facing materials; and engage with ICER review processes and the US policy landscape as relevant to Systemic Mastocytosis and emerging assets.
• Partner with US Medical Affairs, Value & Access, and Policy teams to ensure appropriate use of HEOR evidence in field communications, payer engagement, and training; collaborate on evidence that informs value frameworks, PDAB and ICER responses, and value-based contracting strategies; and mentor junior colleagues on a case-by-case basis, sharing US HEOR and market access expertise.

About You

Basic Qualifications

Education:

• Advanced degree (PhD, PharmD, or equivalent) in health economics, epidemiology, public health, economics, or a related field; or Master's degree in a related field + minimum 4-5+ years of relevant HEOR/outcomes research experience

Experience:

• Completion of a relevant fellowship or minimum of 2+ years of experience in health economics, outcomes research, or a related field

Technical Skills:

• Foundational knowledge in health economic modeling, real-world evidence generation, evidence synthesis, and outcomes research methodologies.
• Understanding of global health technology assessment processes and payer decision-making frameworks.
• Foundational knowledge of AI and digital tools relevant to health economics, including familiarity with data analytics platforms and digital research tools; demonstrated willingness to rapidly develop proficiency with new digital and AI-enabled solutions.

Soft Skills:

• Strong written and verbal communication skills with ability to present technical information clearly to diverse audiences
• Good project management skills with ability to manage timelines and deliverables while staying on budget
• Entrepreneurial spirit, team orientation, and ability to develop creative solutions to complex problems

• Bring the miracles of science to life alongside a supportive, future-focused team
• Discover opportunities to grow your talent and drive your career, whether through a promotion or lateral move, at home or internationally
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs, and at least 14 weeks' gender-neutral parental leave

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SG #LI-GZ #LI-Onsite #vhd All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.