Senior Program Manager, Global Medical Affairs - Rare Disease & General Medicine

Let’s do this. Let’s change the world. In this vital role you will support the development and execution of Medical Strategy for Global Rare Disease and General Medicine Medical Affairs teams, including Dazodalibep and olpasiran. This is a key role whose overarching objective is to drive the development and execution of Medical Strategy in collaboration with Medical Affairs Leads. In this vital role, you will ensure that key deliverables including medical plans, insights, budgets and goals are brought to completion. The Senior Manager is a cross-functional, collaborative role across global, regional, and local Medical teams and partners. You will identify metrics, progress, interdependencies, and concerns, facilitate resolution as needed, and keep the Medical Affairs Team aligned around its priorities. You will lead cross-functional planning, manage project risks, and drive resolution of complex issues while aligning strategic goals across the broader organization.

Responsibilities

• Drive the coordination and integration of insights in partnership with the Medical Affairs Lead to inform product strategy for global and local teams.

• Be a key point of communication to ensure execution of the Medical Plan, including goal development and regular progress tracking.

• Drive the Medical Plan process and ensure alignment between global, regional, and local Medical leads, including large and ROW/emerging markets.

• Understand the Global Medical Strategy and ensure integration through close partnership with EGT, AUEG, IBT and other critical cross-functional partners.

• Drive decision making within the Global Medical Affairs Team and ensure decisions, actions, and follow-up are clearly documented.

• Identify key deliverables for each function and their interdependencies; maintain integrated plans

• Implement standard methodologies and reinforce cross-functional alignment and accountability.

• Identify project issues, risks, and resource gaps; facilitate resolution, contingency planning, and escalation as appropriate.

• Reinforce sound decision making according to Amgen’s Decision-Making Framework.

• Monitor and communicate progress, adherence to timelines, and variance from plan to Medical Affairs leadership.

• Facilitate resource planning, financial planning, and capacity assessments in partnership with Medical Operations, Finance, and functional leaders.

• Conduct risk management, contingency, and scenario planning using a variety of project-management tools.

• Support continuous improvement of Rare Disease & General Medicine Medical planning, governance, and ways of working.

• Drive operational excellence and automation by applying approved emerging technologies, including AI tools such as Copilot, to strengthen Medical planning, reporting, and ways of working.

• 5+ years of project or program-management experience in pharmaceutical, biotechnology, healthcare, or another complex, regulated environment.

• 8+ years of industry experience in biotechnology, pharmaceutical, or healthcare fields.

• Experience supporting Global Medical Affairs, Medical Operations, Finance, Scientific Communications, or cross-functional product teams.

• Experience supporting Rare Disease, General Medicine, specialty, or other complex therapeutic-area portfolios.

• Experience in a role requiring broad communication across multiple groups, levels, and interest groups, with responsibility for influencing change and results.

• Experience leading global, cross-functional initiatives and influencing stakeholders across functions, geographies, and leadership levels without direct authority.

• Experience tracking risks to project completion, including prioritizing, managing resolution, and communicating partner concerns.

• Comfort working through ambiguity and helping create structure when priorities, ownership, or next steps are still evolving. This includes asking thoughtful questions, identifying options, proposing next steps, and helping the team move from discussion to action.

• Experience with integrated planning, milestone tracking, resource planning, financial planning, capacity assessments, and executive-level communication.

• Experience tracking projects in Excel, OneNote, SharePoint, or electronic dashboard and reporting tools.

• Technical fluency with SharePoint, CoPilot, Teams, and dashboard/reporting tools.

• Experience with and curiosity about AI and emerging technologies, with a demonstrated interest in advancing practical solutions to business challenges

What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.