Senior Scientist: Bispecifics and Antibody Engineering
About the role
We are seeking a results-driven Senior Scientist to join Regeneron’s Antibody Engineering team within the Bispecifics and Antibody Engineering Department. In this fast-paced, innovative group, you will design, produce, and characterize next-generation antibody and protein therapeutics across multiple therapeutic areas with a focus on myeloid cell biology. Your work will directly contribute to the pipeline and help build new platform capabilities at a pivotal time for antibody engineering.
As a Senior Scientist, a typical day could require the following:
- Apply molecular and structural biology expertise to independently design innovative multi-specific antibodies with desired potency, selectivity and developability.
- Perform molecular and structural-guided design, high-throughput construct generation, and vector engineering using modern software and tools.
- Produce and purify novel and logic-gated alternative format antibodies using mammalian expression systems utilizing an assortment of molecular biology & biochemical techniques (i.e. AKTA systems and other chromatographic columns).
- Characterize binding affinities, binding kinetics & stability.
- Design and implement high-throughput and properly controlled biochemical and cell-based assays (ELISA and AlphaLISA, flow cytometry binding, phagocytic assays, cell activation and cytolytic assays).
- Troubleshoot bioanalytical and cell-based assay data to inform subsequent iterations.
- Engage program stakeholders to communicate biologic designs with data updates to meet program objectives.
- Clearly convey results to management during cross-departmental meetings and maintain timely, accurate entries using Benchling and research ELN.
This role may be a strong fit If You
- Have expertise in myeloid, molecular, and protein biology.
- Learn new skills quickly and troubleshoot antibody production and functional assays effectively.
- Excel in data analysis and interpretation while supporting multiple projects simultaneously.
- Competently prioritize efforts to quickly adapt to evolving program directions.
- Possess exemplary organizational, communication, and presentation skills.
- Enjoy collaborating across diverse, cross-functional teams.
To be considered for this role you must have
Salary Range (annually)
Not included in the source posting: about the role, qualifications, benefits.
Skills
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