Senior Scientist, Target Discovery & Biology - Functional Genomics

Let’s do this. Let’s change the world. In this vital role you will join the Target Discovery & Biology team in South San Francisco. This role will leverage functional genomics in disease-relevant systems, including complex biological models from in vitro to in vivo , to advance target discovery and validation across Amgen’s therapeutic areas.

Key Responsibilities

• Leverage functional genomics approaches across therapeutic areas to discover novel targets and address key biological questions
• Lead, support and execute projects from inception through target identification, validation and mechanism-of-action studies
• Foster a collaborative, creative, and scientifically rigorous team culture committed to delivering impact across Amgen’s pipeline

• Strong experience in molecular biology and cell engineering. Experience in complex and co-culture in vitro models is a major plus
• Experience in executing large scale, complex, and/or in vivo genetic screens (particularly CRISPR-based) and follow up validation studies. Track record of pushing the envelope on scale and technical feasibility is highly desirable
• Familiarity with data-driven discovery approaches, including integration of genetic or multi-omics insights
• Excellent organizational and communication skills, with the ability to drive cross-site collaboration in a matrixed research environment
• Additional experience relevant to applying functional genomics approaches to new target discovery across diverse indications
• Track record of scientific productivity and innovation as demonstrated through career experiences, project outcomes and/or publications
• Track record of taking on new areas of research and biology with successful outcomes

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.