SERM Medical Director

• Lead pharmacovigilance and risk management activities for assigned oncology assets and clinical trials

• Define and drive strategy for the evaluation and management of safety issues across the clinical development lifecycle

• Analyse   and interpret clinical data, literature, and emerging evidence to   identify   and assess safety signals

• Provide expert medical input into the safety components of global regulatory submissions

• Apply sound clinical judgement to complex and sometimes conflicting data sets to inform benefit–risk decisions

• Ensure   timely   escalation of safety concerns in line with governance processes

• Represent Safety on cross-functional Clinical Matrix and Project Teams

• Lead cross-functional teams to address urgent and complex product safety issues

• Actively contribute to and, where   appropriate , lead Safety Review Teams (SRTs)

• Build strong, collaborative relationships across functions and geographies

• Coach and mentor colleagues, contributing to capability development within the   organisation

• Ensure effective communication and alignment with Safety Leads, senior SERM leadership, and key stakeholders

• Lead presentations on safety issues and recommendations to senior governance committees

• Influence decision-making through clear, credible, and evidence-based communication

• Represent GSK in interactions with regulatory authorities, external experts, and partners

• Contribute to the development of safety strategy for clinical   programmes   and broader SERM activities

• Identify   opportunities to improve processes, drive innovation, and enhance operational effectiveness

• Operate with strong awareness of the internal and external regulatory and scientific environment

This is an opportunity to play a pivotal role in advancing GSK’s oncology pipeline, with   direct   impact on patient safety and global health outcomes.

You will:

• Shape the safety strategy of innovative oncology medicines

• Engage with senior governance and influence key development decisions

• Work within a highly collaborative, global matrix environment

• Contribute to scientific excellence and continuous improvement in safety science

• Medical degree with current GMC registration (or eligibility to   practise   in the UK) and relevant clinical experience

• Completion of formal postgraduate clinical training (e.g., residency or specialty training)

• Significant experience   in pharmacovigilance, drug safety, or medical affairs

• Demonstrated   expertise   in signal detection, evaluation, and risk management

• Strong understanding of clinical development and post-marketing safety processes

• Experience working effectively in matrixed, cross-functional environments

• Excellent written and verbal communication skills, including preparation of medical and regulatory documents

• Strong clinical judgement and the ability to deliver clear, evidence-based recommendations

• Postgraduate   specialisation   in a clinical discipline or pharmaceutical medicine

• Experience contributing to regulatory submissions and periodic safety reports

• Knowledge of epidemiology, biostatistics, or real-world evidence relevant to safety assessment

• Experience leading Safety Review Teams or acting as safety lead for major   programmes

• Prior engagement with regulatory authorities and external safety forums

• Demonstrated ability to coach and develop colleagues in medical, scientific, or safety roles

Working Model This role is hybrid, based in the United Kingdom. You will be expected on site for key meetings, governance activities and team collaboration. Remote working is supported to balance focused work and stakeholder engagement.

How to apply If this role speaks to you, please apply with your CV and a short note describing a safety assessment or risk management activity you led and its impact. If you need reasonable adjustments to apply or interview, tell us and we will support you. We welcome candidates from many backgrounds and encourage you to apply.