Senior Marketing Manager, Global Marketing – Oncology (LUMAKRAS)

• Lead global marketing workstreams supporting development, refinement, and execution of the LUMAKRAS global brand strategy across NSCLC and CRC.

• Translate customer, market, competitive, clinical, and affiliate insights into clear strategic implications, choices, and recommendations for the brand.

• Partner with the Global Marketing Director and cross functional stakeholders to identify emerging opportunities, challenges, and strategic considerations across the LUMAKRAS lifecycle.

• Continuously assess assumptions underlying the brand strategy and recommend adjustments as the treatment landscape, evidence base, customer behaviors, and competitive environment evolve.

• Help define where and how LUMAKRAS can create differentiated value across indications and markets, connecting strategic choices to measurable business objectives.

• Support global launch strategy and readiness workstreams across anticipated first line NSCLC and CRC indications.

• Help shape strategies that address the distinct adoption challenges of each market, including increasing competitive intensity in NSCLC and treatment practice and behavior barriers that may affect adoption in CRC.

• Translate launch strategy into clear critical success factors, key decisions, risks, mitigation plans, and global deliverables.

• Partner across Marketing, Medical, Value & Access, Commercial Excellence, Regions, and Affiliates to integrate functional and market perspectives into global launch planning.

• Support global to local launch readiness by ensuring markets have the strategic direction, insights, resources, and global guidance needed to develop locally relevant launch plans.

• Capture and apply launch learnings across markets to continuously strengthen global strategy and execution.

• Maintain a strong understanding of evolving NSCLC and CRC treatment landscapes, customer behaviors, competitive developments, and market dynamics and assess their implications for LUMAKRAS strategy.

• Partner with Competitive Intelligence, Commercial Data and Analytics, Medical, regional teams, and affiliates to identify emerging developments that could materially affect launch strategy, positioning, or execution.

• Translate insights into strategic recommendations, scenarios, and potential responses that enable the organization to anticipate changes in the market.

• Lead or support strategic workshops, market working sessions, and scenario planning designed to pressure test assumptions and strengthen brand and launch strategy.

• Lead or support evolution of LUMAKRAS positioning strategy and messaging as clinical evidence, competitive profiles, customer insights, and market dynamics evolve.

• Ensure messaging remains grounded in approved evidence and aligned with the broader brand strategy and intended customer behavior change.

• Partner with Medical, Regulatory, Legal, and other appropriate stakeholders to develop and refine global communication frameworks and resources.

• Ensure changes to positioning and messaging are informed by clear strategic rationale rather than developed as standalone communication exercises.

• Build strong partnerships with regional and affiliate marketing teams to incorporate relevant market perspectives and insights into global strategy and launch planning.

• Manage LUMAKRAS Integrated Brand Team and Brand Working Group meetings, including meeting planning, agenda development, coordination of strategic discussions, and follow through on decisions and actions.

• Facilitate alignment, sharing of launch learnings, and exchange of best practices across functions and markets.

• Develop global guidance and strategic resources that enable affiliates to translate global strategy into locally relevant plans.

• Manage agency partners, project plans, budgets, timelines, and deliverables across assigned workstreams.

• Leverage AI enabled tools, analytics, and digital technologies where appropriate to strengthen insight generation, strategic planning, and operational efficiency.

• Manage multiple complex workstreams simultaneously while maintaining quality, strategic focus, and responsiveness to changing business needs.

• Foster a collaborative, inclusive, and engaging team environment that encourages trust, accountability, and shared success.

• Build strong relationships across functions, regions, and affiliate markets that promote teamwork and accelerate execution.

• Contribute to a culture of continuous learning, strategic curiosity, and improvement.

• Proactively identify opportunities, solve problems, and support colleagues across the organization.

• Model Amgen Values through collaboration, integrity, accountability, inclusion, and a commitment to delivering for patients.

• MBA or advanced degree in Business, Marketing, Life Sciences, or a related field.

• Pharmaceutical or biotechnology commercial experience, including global and/or regional marketing.

• Experience supporting in-line brands through lifecycle management and evidence-driven commercialization.

• Demonstrated ability to translate scientific and clinical evidence into compelling commercial strategies and customer-focused marketing messages.

• Experience working effectively across international markets and diverse cultures.

• Strong strategic thinking, project leadership, and execution skills.

• Demonstrated success leading complex cross-functional initiatives and influencing without direct authority.

• Excellent written, verbal, and presentation communication skills.

• Strong organizational skills with the ability to manage multiple priorities in a fast-paced environment.

• Experience partnering with external agencies and managing complex projects from concept through implementation.

• Proficiency with Microsoft Office applications and AI-enabled productivity tools.

• Curious, collaborative, adaptable, and committed to continuous improvement with a passion for delivering meaningful impact for patients.

The successful candidate will embrace opportunities beyond their defined responsibilities, adapting to changing business priorities and contributing wherever they can have the greatest impact across the General Medicine portfolio

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

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