Medical Director/ Senior Patient Safety Physician

At

, we’re dedicated to being a

. Here, you’re empowered to push the boundaries of science, unleash your entrepreneurial spirit, and make a meaningful difference to medicine, patients, and society. We foster an inclusive culture built on diversity, collaboration, and a commitment to lifelong learning, growth, and development. Join

in

as a

and play a pivotal role in shaping the safety strategy behind innovative medicines that can transform patients’ lives. This is a high-impact leadership role for an experienced physician with deep expertise in

,

, and

. You will lead the

for assigned AstraZeneca drug projects and products across all stages of development and, where relevant, in the post-marketing setting.

You’ll work with key internal and external stakeholders, provide scientific leadership, and influence safety strategies that matter to patients around the world. The role offers broad exposure across

, with insight into how strategic direction is shaped within the clinical organisation and how critical decisions are made throughout the drug development lifecycle. Working closely with cross-functional teams in

, you will bring complex issues into clinical context and support informed, science-based decisions. It is also an excellent opportunity to continue growing your expertise in

,

, and

within a global, innovation-driven environment.

You will lead the clinical safety strategy for assigned products and programs, representing both the

and

perspective. You will provide senior medical expertise on the safety profile of products and disease areas, ensuring robust and proactive safety assessment throughout development and post-marketing. Your responsibilities will include: •

for assigned projects and products, including implementation and communication at project team and governance level •

for AstraZeneca products or product groups in clinical development and/or the post-marketing setting •

to help predict, characterise, and manage the safety profile of compounds and marketed products •

and driving proactive

in line with global regulatory requirements •

, proposing mitigation and minimisation measures, and contributing to safety go/no-go criteria, submission strategies, and benefit-risk assessments •

, including

, renewal documentation, and other regulatory safety reports •

across regulatory documents and contributing to responses to regulatory authority questions and labelling updates •

, including medical review of individual safety cases where appropriate •

and other product safety documentation •

, including

submissions for new products, formulations, or indications •

through strategic safety input into project-specific safety requirements, investigator brochures, protocols, informed consent documents, final study reports, and data monitoring committee materials as appropriate •

, including colleagues in Patient Safety, Clinical Development, Regulatory Affairs, pre-clinical safety, safety science, and safety informatics •

, governance discussions, inspection and audit readiness, process improvement initiatives, and mentoring junior colleagues where relevant

•

such as

or

, with the majority ideally gained in

, particularly

and

and

and

or a related discipline

Our purpose is ambitious, and so is our approach. Becoming a more agile and innovative company means building a dynamic, inspiring culture where we celebrate forward thinking and act with urgency. We are ambitious, take informed risks, and learn from both success and failure. We are curious, creative, and open to new ideas and ways of working. Above all, we are passionate about science and driven to always put patients first. If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do, we’d love to hear from you. Join us and be part of an outstanding place to work — an environment that energizes and empowers each of us to achieve our personal and organizational goals.

Ready to take the next step? Please submit your

no later than

. To help us review your application smoothly, please combine your

before uploading.

13-aug.-2026

31-aug.-2026 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.